Your mouth is connected to the rest of your body. Did you know that your oral health can offer clues about your overall health — or that problems in your mouth can affect the rest of your body? Your mouth is connected to the rest of your body. To understand how the mouth can affect the body, it helps to understand what can go wrong in the first place. Bacteria that builds up on teeth make gums prone to infection. The immune system moves in to attack the infection and the gums become inflamed. The inflammation continues unless the infection is brought under control.